Key result
In patients with type I diabetes and nephropathy, abnormal heart rate variations occurred during respiratory cycles in 56%, posture changes in 38%, and Valsalva maneuver in 38%.
Why the study?
What is the prevalence of autonomic dysfunction and its correlation with cardiac risk factors in type I diabetics with established nephropathy?
Population
42 type I diabetics with established nephropathy
Design
Cross-sectional
Authors
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Autonomic dysfunction is common in type 1 diabetes with nephropathy; hypothesis-generating for cardiac risk links pending prospective data.
Cross-Sectional (n=42)
What is the prevalence of autonomic dysfunction and its correlation with cardiac risk factors in type I diabetics with established nephropathy?
Autonomic dysfunction, including abnormal heart rate variations and blunted day/night blood pressure ratios, is highly prevalent in type I diabetics with established nephropathy.
Weinrauch et al. (1995) conducted a cross-sectional in type I diabetes mellitus complicated by nephropathy (n=42). Type I diabetes with nephropathy was evaluated on prevalence of parasympathetic and sympathetic autonomic dysfunction. In patients with type I diabetes and nephropathy, abnormal heart rate variations occurred during respiratory cycles in 56%, posture changes in 38%, and Valsalva maneuver in 38%.
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