Why the study?
Do thiopental, etomidate, and propofol alter regional myocardial function in normal and acute ischemic heart segments in dogs?
Population
Dogs with normal and acute ischemic heart segments
Design
Preclinical
Follow-up
30 minutes
Authors
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Thiopental may impair ischemic segments more than etomidate in this canine model; leaves open translation to human anesthetic selection.
Do thiopental, etomidate, and propofol alter regional myocardial function in normal and acute ischemic heart segments in dogs?
In a canine model, etomidate maintains regional myocardial function, whereas thiopental disproportionately depresses function in acutely ischemic segments compared to normal segments.
Hert et al. (1990) studied this question.
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