Population
Rat portal vein
Comparison
Hyperosmolality (HC) induced contracture vs K+-induced contractures, normal isotonic…
Design
Preclinical
Follow-up
30 min
Authors
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Similar cross-bridge energetics in hypertonic vs K+ contractures despite metabolic shifts; hypothesis-generating for cardiac muscle and requires human validation.
Despite alterations in overall cell metabolism caused by hypertonic solution, the energetic aspects of cross-bridge operation in rat portal vein contracture appear similar to K+-induced contracture.
Arner et al. (1980) studied this question.
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