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September 1, 1980Acta Physiologica Scandinavica

Contraction of the rat portal vein in hypertonic and isotonic medium: mechanical properties and effects of Mg2+

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Population

Rat portal vein

Comparison

Hyperosmotic solutions (HC) vs K+-induced contractures and passive stretch

Design

Preclinical

Authors

PHPer HellstrandLund UniversityAAAnders ArnerLund University

Discussion

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Implication

Animal data on rat vein contracture mechanisms remain hypothesis-generating; leaves open translation to human vascular physiology or practice.

Structured PICO

P
Population
Rat portal vein
I
Intervention
Hyperosmotic solutions (HC)
C
Comparator
K+-induced contractures (KC) and passive stretch (PS)
O
Outcome
Mechanical properties and Mg2+-dependence of contracturesurrogate

Hyperosmotic contracture in the rat portal vein originates in the contractile system and exhibits distinct mechanical properties and Mg2+ dependence compared to K+-induced contracture.

Cite This Study

Hellstrand et al. (1980) studied this question.

synapsesocial.com/papers/6a86f29948ef9afcd2a250b6https://doi.org/10.1111/j.1748-1716.1980.tb06630.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characteristics of Ca2+- and Mg2+-induced tension development in chemically skinned smooth muscle fibers.1978 · 194 citations
  2. 2Contraction of the rat portal vein in hypertonic and isotonic medium: rates of metabolism1980 · 17 citations
  3. 3Contraction in Venous Smooth Muscle Induced by Hypertonicity. Calcium Dependence and Mechanical Characteristics1974 · 33 citations
  4. 4Analysis of the length response to a force step in smooth muscle from rabbit urinary bladder1979 · 70 citations
  5. 5Hyperosmolarity: effects on nerves and smooth muscle of cutaneous veins1976 · 32 citations