Why the study?
Does biosynthetic growth hormone improve height velocity in children with hypochondroplasia?
Population
84 patients with hypochondroplasia for the growth study; 20 children aged 4.3 to 12.8 years with normal…
Comparison
Biosynthetic growth hormone in doses between… vs Pretreatment baseline
Design
Cohort
Authors
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May support growth hormone for height velocity in hypochondroplasia; leaves open randomized confirmation of sustained benefit.
Does biosynthetic growth hormone improve height velocity in children with hypochondroplasia?
Biosynthetic growth hormone therapy significantly accelerates short-term height velocity in children with hypochondroplasia.
Appan et al. (1990) studied this question.
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