Why the study?
Does intraluminal pressure differ between proximal and distal sites adjacent to left colonic anastomoses?
Does intraluminal pressure differ between proximal and distal sites adjacent to left colonic anastomoses?
Intraluminal pressures are unlikely to play a role in anastomotic dehiscence, despite distal peak pressures being significantly elevated compared to proximal sites.
Answers are grounded in this paper and cite their sources.
Intraluminal pressures unlikely to drive anastomotic dehiscence; leaves open alternative mechanisms in left colonic surgery.
A cumulative total of 89 h of pressure data was acquired from both sides of a left colonic anastomosis in 15 patients over a median period of 7 postoperative study days. Patients had a colonic ileus lasting 3-10 days and during this proximal and distal inactivity the intraluminal pressure remained within 6 mmHg of atmospheric pressure. After recovery of activity, pressures proximal to the anastomosis in excess of 10 mmHg occurred during less than 1 per cent of the recording time. Distal peak pressures were significantly elevated with respect to the proximal site (P less than 0.001). Two-thirds of the distal pressures recorded were between 10 and 20 mmHg and 98 per cent were less than 50 mmHg; the peak distal pressure was 90 mmHg. Four patients had distal repetitive tonic contractions creating a pressure difference across the anastomosis with a mean of 20 mmHg and a peak of 45 mmHg. Each contraction persisted for 15-20 min. Intraluminal pressures are unlikely to play a role in anastomotic dehiscence.
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Burkitt et al. (1990) studied this question.
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