Key result
In children with acute Kawasaki disease, log-transformed BNP concentration was significantly associated with serum albumin concentration (R2=0.31, P=0.0098) and left ventricular mass index (R2=0.09, P=0.0004).
Why the study?
Is log-transformed BNP quantitatively associated with myocardial dysfunction in children with acute phase Kawasaki disease?
Cross-Sectional (n=81)
No
Is log-transformed BNP quantitatively associated with myocardial dysfunction in children with acute phase Kawasaki disease?
Effect estimate: R2=0.31
p-value: p=0.0098
Log-transformed BNP is quantitatively associated with serum albumin and left ventricular mass index, suggesting it may serve as a biochemical marker of myocarditis and cardiac dysfunction in the acute phase of Kawasaki disease.
No takes yet. Share an insight, caveat, or question.
May mark acute myocardial involvement in Kawasaki disease; hypothesis-generating and requires prospective validation before clinical use.
Bang et al. (2011) conducted a cross-sectional in Kawasaki disease (n=81). Log-transformed brain natriuretic peptide (log-BNP) was evaluated on Variables independently associated with log-BNP concentration (R2=0.31, p=0.0098). In children with acute Kawasaki disease, log-transformed BNP concentration was significantly associated with serum albumin concentration (R2=0.31, P=0.0098) and left ventricular mass index (R2=0.09, P=0.0004).
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