Why the study?
Are abnormal tissue Doppler imaging profiles associated with elevated plasma BNP and increased oxidative stress in acute Kawasaki disease?
Are abnormal tissue Doppler imaging profiles associated with elevated plasma BNP and increased oxidative stress in acute Kawasaki disease?
Abnormal myocardial mechanics detected by tissue Doppler imaging in acute Kawasaki disease correlate with elevated BNP and oxidative stress, suggesting latent systolic and diastolic dysfunction.
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May signal subclinical dysfunction in acute KD; hypothesis-generating and requires prospective validation before clinical use.
Takeuchi et al. (2007) studied this question.
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