Why the study?
What are the volume-regulatory and endocrine responses to blood loss in humans?
Population
Humans experiencing blood loss or hemorrhage
Design
Review
Authors
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Informs compensatory physiology after hemorrhage; leaves open targeted interventions in modern resuscitation trials.
What are the volume-regulatory and endocrine responses to blood loss in humans?
The physiological response to hemorrhage in humans involves transcapillary refilling to restore blood volume and renin-angiotensin-mediated aldosterone hypersecretion.
Skillman et al. (1968) studied this question.
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