Intracardiac Injection of Radioactive Krypton
Why the study?
Does intracardiac injection of radioactive krypton 85 accurately detect and localize cardiac shunts in patients undergoing cardiac catheterization?
Population
68 patients undergoing cardiac catheterization, including 19 without right-to-left shunts, 9 with proved…
Design
Cross-sectional
Authors
Discussion
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Implication
May aid shunt detection during catheterization; leaves open prospective validation before routine use.
Structured PICO
Does intracardiac injection of radioactive krypton 85 accurately detect and localize cardiac shunts in patients undergoing cardiac catheterization?
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Population
68 patients undergoing cardiac catheterization, including 19 without right-to-left shunts, 9 with proved right-to-left shunts, 22 with left-to-right shunts, and 18 injected distal to a left-to-right shunt.
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Intervention
Intracardiac injection of 30 to 50 µc of radioactive krypton 85 in solution.
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Outcome
Radioactivity per milliliter of arterial blood (for right-to-left shunts) and appearance time of Kr 85 in expired gas (for left-to-right shunts).surrogate
Intracardiac injection of radioactive krypton 85 provides a sensitive and simple method for detecting and localizing cardiac shunts during catheterization.
Cite This Study
Long et al. (1960) studied this question.