Why the study?
Does intravenous diazepam followed by nitrous oxide provide stable hemodynamic effects compared to baseline in patients with coronary artery disease undergoing bypass surgery?
Population
14 patients with coronary artery disease undergoing elective aortocoronary saphenous vein bypass operations…
Comparison
Intravenous diazepam continuously infused over a… vs Control awake values and historical data of…
Design
Case_series
Follow-up
Immediate (during and immediately following infusion)
Authors
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May inform induction agent selection in CAD; hypothesis-generating and should not change practice without randomized confirmation.
Does intravenous diazepam followed by nitrous oxide provide stable hemodynamic effects compared to baseline in patients with coronary artery disease undergoing bypass surgery?
Diazepam-nitrous oxide induction produces minimal circulatory changes, making it a hemodynamically stable alternative to morphine-nitrous oxide induction in patients with coronary artery disease.
McCammon et al. (1981) studied this question.
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