Key result
Intravenous diazepam induction (0.5 mg/kg) in patients undergoing CABG caused small, transient, but statistically significant decreases in hemodynamic parameters compared to awake baseline.
Why the study?
Does intravenous diazepam induction of anesthesia alter hemodynamics in patients with ischemic heart disease undergoing CABG?
Population
n=10 patients with ischemic heart disease about to have coronary artery bypass grafting (CABG).
Comparison
Intravenous diazepam 0.5 mg/kg for induction of… vs Awake baseline.
Design
Case_series
Follow-up
During induction of anesthesia
Authors
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May support diazepam induction in CABG; case report leaves open need for prospective validation.
Observational (n=10)
Does intravenous diazepam induction of anesthesia alter hemodynamics in patients with ischemic heart disease undergoing CABG?
Intravenous diazepam induction for CABG causes small, transient, and well-tolerated hemodynamic changes in patients with ischemic heart disease.
Samuelson et al. (1980) conducted an observational in Ischemic heart disease (n=10). Intravenous diazepam vs. Awake baseline was evaluated on Hemodynamic changes (mean arterial pressure, rate pressure product, stroke index, and left and right ventricular stroke work indexed). Intravenous diazepam induction (0.5 mg/kg) in patients undergoing CABG caused small, transient, but statistically significant decreases in hemodynamic parameters compared to awake baseline.
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