Why the study?
Does orthotopic cardiac transplantation improve pulmonary hypertension and right ventricular remodeling in patients with severe congestive heart failure?
Population
24 recipients of orthotopic cardiac transplants with severe congestive heart failure and secondary pulmonary…
Comparison
Orthotopic cardiac transplantation vs Preoperative baseline
Design
Cohort
Follow-up
1 year
Authors
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Supports transplant-associated hemodynamic gains in severe HF; extends observational data but leaves open outcome effects.
Does orthotopic cardiac transplantation improve pulmonary hypertension and right ventricular remodeling in patients with severe congestive heart failure?
Orthotopic cardiac transplantation leads to rapid resolution of moderately elevated pulmonary arterial pressures and sustained right ventricular enlargement with decreased tricuspid regurgitation at 1 year.
Bhatia et al. (1987) studied this question.
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