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April 12, 2004Journal of VirologyOpen Access

Functional and Structural Similarities between the Internal Ribosome Entry Sites of Hepatitis C Virus and Porcine Teschovirus, a Picornavirus

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Authors

APAndrey V. PisarevClinical Solutions LCLouisa S. ChardQueen Mary University of London YKYoshihiro KakuNational Institute of Infectious Diseases

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Implication

280-nt PTV-1 IRES supports efficient initiation; leaves open compact vector applications pending validation.

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Cite This Study

Pisarev et al. (2004) studied this question.

synapsesocial.com/papers/6a922be73da4caa5ce96304f https://doi.org/10.1128/jvi.78.9.4487-4497.2004

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A Phylogenetically Conserved Stem-Loop Structure at the 5′ Border of the Internal Ribosome Entry Site of Hepatitis C Virus Is Required for Cap-Independent Viral Translation1999 · 255 citations
2Mechanism of ribosome recruitment by hepatitis C IRES RNA2001 · 375 citations
3Activity of the Hepatitis A Virus IRES Requires Association between the Cap-Binding Translation Initiation Factor (eIF4E) and eIF4G2001 · 129 citations
4A complex RNA sequence detemines the internal initiation of encephalomyocarditis virus RNA translation1991 · 54 citations
5Interaction of the eIF4G initiation factor with the aphthovirus IRES is essential for internal translation initiation in vivo2000 · 142 citations