Why the study?
Does dorsal root section reduce ectopic beats associated with short-lasting coronary artery occlusions in anesthetized dogs and cats?
Population
Anesthetized vagotomized dogs and cats (n=12) undergoing brief coronary artery occlusion (5-90 s)
Comparison
Dorsal root section from C8 to T5 vs Repeated occlusions without dorsal root section
Design
Preclinical
Follow-up
60 seconds following release of occlusion
Authors
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Animal data support sympathetic reflex role in ischemia ectopy; leaves open translation to human arrhythmia prevention.
Does dorsal root section reduce ectopic beats associated with short-lasting coronary artery occlusions in anesthetized dogs and cats?
Dorsal root section significantly reduces ectopic beats during brief coronary occlusion in animal models, suggesting a role for the cardiocardiac sympathetic reflex in ischemia-induced arrhythmias.
Pj et al. (1976) studied this question.
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