May 1, 1950Experimental Biology and Medicine

Partial Purification of Viruses with an Anion Exchange Resin.

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Population

Lansing strain of poliomyelitis virus from nervous tissue of mice, poliomyelitis virus from human feces, and…

Design

Preclinical

Authors

GLGerald A. LoGrippoDetroit R&D (United States)

Discussion

Member takes

Implication

May simplify virus purification in research models; hypothesis-generating and should not yet change practice.

Structured PICO

Population

Lansing strain of poliomyelitis virus from nervous tissue of mice, poliomyelitis virus from human feces, and Theiler virus from feces of normal mice. Assayed in 4-5 and 3-4-week-old mice (CFW-albino agouti strain) and monkeys (Macaca mulatta).

Intervention

Partial purification using strong-base anion exchange resin (Amberlite XE-67 in chloride exchange form)

Outcome

Virus purification (elimination of extraneous material without significant loss of virus)

Amberlite XE-67 anion exchange resin provides a rapid and simple method for the partial purification of poliomyelitis and Theiler viruses.

Cite This Study

Gerald A. LoGrippo (1950) studied this question.

synapsesocial.com/papers/6a923563ca631ded646759c8 https://doi.org/10.3181/00379727-74-17856

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Partial Purification of Viruses with an Anion Exchange Resin.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Partial Purification of Viruses with an Anion Exchange Resin.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider