Why the study?
Are PAF-AH gene polymorphisms associated with carotid intima-media thickness in hypercholesterolemic individuals?
Population
190 hypercholesterolemic Sicilian individuals
Design
Cross-sectional
Authors
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Does not support PAF-AH polymorphisms as carotid IMT markers in hypercholesterolemia; leaves open their role in atherosclerosis risk research.
Are PAF-AH gene polymorphisms associated with carotid intima-media thickness in hypercholesterolemic individuals?
PAF-AH gene polymorphisms (Arg92His, Ile198Thr, Ala379Val) do not appear to influence PAF-AH activity or carotid atherosclerosis in hypercholesterolemic Sicilian patients.
Campo et al. (2004) studied this question.
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