High-dose quinidine successfully suppressed idiopathic recurrent parasystolic ventricular tachycardia in a pediatric patient without organic heart disease.
High-dose quinidine may control refractory pediatric parasystolic VT; single case leaves open generalizability and safety.
An asymptomatic 3 1/2-year-old boy demonstrated parasystolic ventricular tachycardia with AV dissociation, early sinus capture beats, marked variability in coupling intervals between conducted and ectopic beats, fusion beats, and interectopic intervals which were multiples of the ectopic cycle length. The arrhythmia initially responded to quinidine, reappeared over an 11-month observation period, and finally was suppressed at a high quinidine dose. An invasive and noninvasive work-up failed to demonstrate organic heart disease.
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Lightfoot et al. (1983) studied this question.
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