Why the study?
Does nicotinic acid reduce plasma glucose concentration in normal individuals?
Population
Normal individuals
Comparison
Continuous four-hour infusions of nicotinic acid… vs Continuous four-hour infusion of 0.9% NaCl or…
Follow-up
4 hours
Authors
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Nicotinic acid may lower glucose in healthy subjects; hypothesis-generating and should not yet inform practice.
Does nicotinic acid reduce plasma glucose concentration in normal individuals?
Nicotinic acid lowers plasma glucose concentration in normal volunteers, likely mediated by a decrease in plasma non-esterified fatty acid concentration.
Landau et al. (1992) studied this question.
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