Why the study?
Does pentoxifylline reduce proinflammatory cytokine release in patients undergoing coronary artery bypass graft surgery?
Population
30 patients undergoing coronary artery bypass graft surgery
Comparison
Pentoxifylline continuous infusion of 1.5 mg/kg… vs No pentoxifylline (control group)
Design
RCT, randomized
Follow-up
5 different time points during/after operation
Authors
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Pentoxifylline blunts post-CPB cytokine surge in CABG; confirms anti-inflammatory effect in RCT and supports outcome trials.
Does pentoxifylline reduce proinflammatory cytokine release in patients undergoing coronary artery bypass graft surgery?
Pentoxifylline infusion during cardiac surgery significantly inhibits the proinflammatory cytokine release caused by cardiopulmonary bypass.
Işkesen et al. (2006) studied this question.
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