Key result
Bi-phasic transmittance waveform analysis identified disseminated intravascular coagulation with 97.6% sensitivity and 98% specificity, preceding abnormalities in standard laboratory tests.
Why the study?
Does transmittance waveform analysis accurately and early identify disseminated intravascular coagulation compared to standard laboratory tests?
Population
747 patients, including 41 with disseminated intravascular coagulation (DIC)
Comparison
Transmittance waveform analysis vs Standard laboratory tests for DIC
Design
Cohort
Authors
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May aid earlier DIC detection in observational cohorts; leaves open prospective outcome validation before practice change.
Observational (n=747)
Does transmittance waveform analysis accurately and early identify disseminated intravascular coagulation compared to standard laboratory tests?
Transmittance waveform analysis of the APTT assay provides a highly sensitive and specific early diagnostic marker for disseminated intravascular coagulation.
Kazmi et al. (1998) conducted an observational in Disseminated intravascular coagulation (DIC) (n=747). Transmittance waveform analysis (bi-phasic waveform pattern) vs. Standard laboratory tests was evaluated on Diagnosis of DIC. Bi-phasic transmittance waveform analysis identified disseminated intravascular coagulation with 97.6% sensitivity and 98% specificity, preceding abnormalities in standard laboratory tests.
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