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This review discusses recent findings on how the G protein-coupled potassium channel (GIRK) signalling complex is spatially arranged and activated in intact cells using fluorescence-based approaches.
This review highlights the use of fluorescence-based approaches to understand the spatial compartmentalization and activation mechanisms of the GIRK channel by G proteins.
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Fluorescence mapping advances GIRK compartmentalization models; leaves open clinical translation to arrhythmia therapies.
Raveh et al. (2009) conducted a review in G protein-coupled receptor (GPCR)-mediated signalling. This review discusses recent findings on how the G protein-coupled potassium channel (GIRK) signalling complex is spatially arranged and activated in intact cells using fluorescence-based approaches.
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