Key result
Existing evidence concerning the effects of obesity on aortic stiffness in patients with arterial hypertension is contradictory and warrants further clarification.
The existing evidence concerning obesity effects on aortic stiffness is contradictory and warrants further clarification.
Contradictory evidence on obesity and aortic stiffness in hypertension precludes firm conclusions; leaves open the need for prospective trials.
Cardiovascular disease (CVD) remains the leading cause of death in most developed countries. Morphological and functional status of large arteries plays an important role in the pathogenesis of CVD. At the moment, there are two main methods of aortic stiffness assessment: pulse wave velocity (PWV) measurement and central PW analysis. In advanced age, aortic stiffness increases, which manifests in increased PWV, elevated central blood pressure, and increased parameters of reflected PW. Similar changes can be observed in young patients with arterial hypertension. The existing evidence concerning obesity effects on aortic stiffness is contradictory and warrants further clarification.
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Shupenina et al. (2013) conducted a review in Arterial hypertension and obesity. Obesity was evaluated. Existing evidence concerning the effects of obesity on aortic stiffness in patients with arterial hypertension is contradictory and warrants further clarification.
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