Key result
Postmortem radioimmunoassay of digoxin from leg veins is valuable for assessing antemortem digitalization, identifying supratherapeutic levels in 5 of 6 cases suspected of digoxin-related death.
Why the study?
Can postmortem radioimmunoassay of digoxin in blood samples accurately assess antemortem digitalization?
Population
Postmortem blood samples from patients previously on maintenance digoxin therapy, including control cases…
Comparison
Postmortem assay of digoxin by radioimmunoassay vs Control cases vs. cases where digoxin was…
Design
Cohort
Authors
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May support forensic digoxin assessment in suspected toxicity; leaves open validation in larger cohorts.
Observational
Can postmortem radioimmunoassay of digoxin in blood samples accurately assess antemortem digitalization?
Postmortem radioimmunoassay of digoxin from leg vein blood samples is valuable for assessing antemortem digitalization and identifying potential digoxin toxicity.
Holt et al. (1975) conducted an observational in Patients previously on maintenance digoxin therapy who died. Postmortem digoxin assay by radioimmunoassay vs. Control cases was evaluated on Postmortem serum digoxin levels. Postmortem radioimmunoassay of digoxin from leg veins is valuable for assessing antemortem digitalization, identifying supratherapeutic levels in 5 of 6 cases suspected of digoxin-related death.
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