Key result
A modified radioimmunoassay for digoxin using an initial dichlormethane extraction achieved a precision of 5-7% and extracted more than 93% of digoxin.
Population
Serum, urine, and homogenized myocardial tissue samples
Design
Other
Authors
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May facilitate pharmacokinetic digoxin studies; leaves open clinical validation before routine use.
A modified radioimmunoassay provides a precise method for measuring digoxin levels in various biological samples, suitable for pharmacokinetic studies.
Axel Brock (1974) studied this question. Modified radioimmunoassay for digoxin was evaluated on Precision of the assay. A modified radioimmunoassay for digoxin using an initial dichlormethane extraction achieved a precision of 5-7% and extracted more than 93% of digoxin.
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