Key result
Transcatheter closure via a surgical transapical approach for paravalvular leaks had 0% in-hospital mortality; surgical treatment was a risk factor for in-hospital death (OR 8; 95% CI 1.8-13; P=0.05).
Why the study?
Does transcatheter closure via a surgical transapical approach reduce in-hospital mortality compared to conventional surgery in high-risk patients with paravalvular leak?
Cohort (n=139)
No
Does transcatheter closure via a surgical transapical approach reduce in-hospital mortality compared to conventional surgery in high-risk patients with paravalvular leak?
Odds Ratio: 8 (95% CI 1.8–13)
p-value: p=0.05
Transcatheter closure via a surgical transapical approach is a safe and effective alternative to conventional surgery for paravalvular leak repair in high-risk patients, associated with lower in-hospital mortality.
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May support transapical transcatheter closure in high-risk paravalvular leak; leaves open randomized confirmation of mortality benefit.
Taramasso et al. (2014) conducted a cohort in Paravalvular leaks (PVL) (n=139). Transcatheter closure via a surgical transapical approach (TAp) vs. Surgical treatment was evaluated on In-hospital death (OR 8, 95% CI 1.8-13, p=0.05). Transcatheter closure via a surgical transapical approach for paravalvular leaks had 0% in-hospital mortality; surgical treatment was a risk factor for in-hospital death (OR 8; 95% CI 1.8-13; P=0.05).
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