Key result
Sublingual captopril and clonidine provide effective acute blood pressure reduction without the severe adverse effects of sublingual nifedipine, reducing its use by 98% at a Veterans Affairs center.
Why the study?
What are safer alternatives to sublingual nifedipine for acute BP reduction in hypertensive urgencies?
Population
Patients with hypertensive urgencies and emergencies
Comparison
Sublingual captopril, oral and sublingual… vs Sublingual nifedipine
Design
Review
Authors
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Sublingual captopril or clonidine may be considered for hypertensive urgencies; leaves open randomized confirmation before practice change.
What are safer alternatives to sublingual nifedipine for acute BP reduction in hypertensive urgencies?
Sublingual captopril and clonidine are safer and effective alternatives to sublingual nifedipine for managing hypertensive urgencies.
Paul R. Matuschka (1999) conducted a review in Hypertensive urgencies and emergencies. Sublingual captopril and clonidine vs. Sublingual nifedipine was evaluated on Acute blood pressure reduction and adverse effects. Sublingual captopril and clonidine provide effective acute blood pressure reduction without the severe adverse effects of sublingual nifedipine, reducing its use by 98% at a Veterans Affairs center.
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