Key result
Heavy endurance training in athletes was associated with a 37% greater maximal blood flow and 48% greater capillary diffusion capacity compared to sedentary controls (P<0.001).
Why the study?
Does heavy endurance training increase capillary diffusion capacity and maximal blood flow in skeletal muscle compared to a sedentary lifestyle?
Observational (n=21)
Does heavy endurance training increase capillary diffusion capacity and maximal blood flow in skeletal muscle compared to a sedentary lifestyle?
Effect estimate: 37% increment in MBF and 48% increment in CDCI
p-value: p=<0.001
Heavy endurance training is associated with increased maximal blood flow and capillary diffusion capacity in skeletal muscle, likely reflecting increased capillary surface area.
May support endurance training for muscle perfusion; leaves open causality and relevance beyond athletes.
The effect of heavy endurance training on capillary diffusion capacity (CDC) and maximal blood flow (MBF) in skeletal muscle was studied in eleven highly-trained athletes and ten sedentary adult volunteers. MBF was estimated from 133Xe clearance and CDCI from 133Xe and 131I- clearances in the anterior tibial muscle after ischaemic exercise. The athletes had a significantly greater MBF, 131I- clearance and CDCI than the control subjects (P less than 0.001). The average increment of MBF was 37% and that of CDCI 48%. Increase in CDC is considered to reflect an increase in capillary surface area due to physical training.
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Leinonen et al. (1978) reported an observational. Heavy endurance training vs. Sedentary adult volunteers was evaluated on Maximal blood flow (MBF) and capillary diffusion capacity (CDC) (37% increment in MBF and 48% increment in CDCI, p=<0.001). Heavy endurance training in athletes was associated with a 37% greater maximal blood flow and 48% greater capillary diffusion capacity compared to sedentary controls (P<0.001).
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