Key result
Poliomyelitis virus was successfully recovered from the nasopharynx of a single patient with suspected abortive poliomyelitis, but not from 26 other cases or 14 contacts.
Why the study?
Can poliomyelitis virus be isolated from the nasopharynx of patients with suspected abortive poliomyelitis?
Case Report (n=41)
Can poliomyelitis virus be isolated from the nasopharynx of patients with suspected abortive poliomyelitis?
The study demonstrates that poliomyelitis virus can be isolated from the nasopharynx of a patient with mild abortive illness and preserved in glycerine for up to 101 days.
Answers are grounded in this paper and cite their sources.
Single-case nasopharyngeal recovery supports sampling feasibility; leaves open diagnostic and transmission roles in abortive poliomyelitis.
A single example of mild illness diagnosed as suspected abortive poliomyelitis is described in which the virus of poliomyelitis was recovered from the nasopharynx by three different methods. Failure to recover virus from a total of twenty-six cases diagnosed as suspected or abortive poliomyelitis and fourteen contacts is also reported. The original material from the nasopharynx of the positive case proved unusually infective for the monkey, apparently even more so than are the majority of suspensions of spinal cords from fatal human cases of poliomyelitis. An explanation of this fact is not clear. The method of isolating human virus from the throat, by means of preserving the sediment of washings from this site in glycerine, has been shown to be efficient in one case for a period of 101 days.
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Paul et al. (1935) conducted a case report in Poliomyelitis (n=41). Virus isolation from the nasopharynx was evaluated on Recovery of poliomyelitis virus. Poliomyelitis virus was successfully recovered from the nasopharynx of a single patient with suspected abortive poliomyelitis, but not from 26 other cases or 14 contacts.
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