Key result
Type I diabetes patients with elevated albumin excretion rate (>15 µg/min) had higher mean 24-hour systolic and diastolic blood pressure than those with normal AER and healthy controls.
Why the study?
Does ambulatory blood pressure differ in adolescents and young adults with type I diabetes and incipient nephropathy compared to those without nephropathy and healthy controls?
Population
74 adolescents and young adults, comprising 38 with type I diabetes and 36 healthy nondiabetic controls.
Comparison
Ambulatory blood pressure monitoring in patients… vs Type I diabetes patients with AER < 15…
Design
Cross-sectional
Follow-up
24 hours
Authors
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May support earlier ambulatory BP monitoring in young type 1 diabetes with elevated AER; leaves open causal links and intervention effects.
Observational (n=74)
Does ambulatory blood pressure differ in adolescents and young adults with type I diabetes and incipient nephropathy compared to those without nephropathy and healthy controls?
Adolescents and young adults with type I diabetes and incipient nephropathy exhibit higher ambulatory blood pressure and a blunted nocturnal blood pressure dip compared to those without nephropathy and healthy controls.
Moore et al. (1992) conducted an observational in Type I Diabetes Mellitus (n=74). Elevated albumin excretion rate (AER > 15 micrograms/min) vs. Type I diabetes with AER < 15 micrograms/min and healthy controls was evaluated on Mean 24-h systolic BP, diastolic BP, and BP burden. Type I diabetes patients with elevated albumin excretion rate (>15 µg/min) had higher mean 24-hour systolic and diastolic blood pressure than those with normal AER and healthy controls.
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