Key result
High normal albumin excretion rate (7-20 µg/min) in children with type 1 diabetes was associated with higher daytime systolic blood pressure compared to low normal AER (118.2 vs 108.8 mm Hg, P=0.02).
Why the study?
Is high normal albumin excretion rate associated with elevated ambulatory blood pressure in children with type 1 diabetes mellitus?
Population
78 children with type 1 diabetes mellitus and normoalbuminuria, mean age 13.4 +/- 2.7 years, mean DM1…
Comparison
High normal albumin excretion rate vs Low normal albumin excretion rate
Design
Cross-sectional
Authors
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May prompt earlier ambulatory BP monitoring in pediatric T1D; hypothesis-generating and requires longitudinal validation before practice change.
Observational (n=78)
Is high normal albumin excretion rate associated with elevated ambulatory blood pressure in children with type 1 diabetes mellitus?
Absolute Event Rate: 118.2% vs 108.76%
p-value: p=0.02
In children with type 1 diabetes, an albumin excretion rate in the high normal range is associated with elevated systolic and diastolic ambulatory blood pressure.
Gallego et al. (2005) conducted an observational in Type 1 diabetes mellitus with normoalbuminuria (n=78). High normal albumin excretion rate (7-20 microg/min) vs. Low normal albumin excretion rate (<= 7 microg/min) was evaluated on Daytime systolic blood pressure (p=0.02). High normal albumin excretion rate (7-20 µg/min) in children with type 1 diabetes was associated with higher daytime systolic blood pressure compared to low normal AER (118.2 vs 108.8 mm Hg, P=0.02).
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