Key result
Nighttime diastolic blood pressure is a significant independent predictor for microalbuminuria (OR 5.608) in children and adolescents with type 1 diabetes.
Why the study?
To examine ambulatory blood pressure characteristics, including blood pressure variability, and their association with albuminuria in children with type 1 diabetes, and to identify potential predictors of high-normal albuminuria and microalbuminuria.
Population
201 T1D children and adolescents (mean age, 14.7±3.8 years) with T1D duration over 1 year
Comparison
Patients classified by albuminuria level as low-normal, high-normal, or microalbuminuria
Design
Cross-sectional study
Authors
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May support ambulatory nighttime BP monitoring for risk stratification in pediatric T1D; hypothesis-generating pending prospective trials.
Cross-Sectional (n=201)
No
Odds Ratio: 5.608 (95% CI 1.985–15.847)
Children and adolescents with type 1 diabetes exhibit impaired blood pressure regulation with elevated nighttime blood pressure, and nighttime diastolic blood pressure is an independent predictor of microalbuminuria.
Morić et al. (2022) conducted a cross-sectional in Type 1 diabetes mellitus (n=201). Nighttime diastolic blood pressure vs. Lower nighttime diastolic blood pressure was evaluated on Microalbuminuria (OR 5.608, 95% CI 1.985-15.847). Nighttime diastolic blood pressure is a significant independent predictor for microalbuminuria (OR 5.608) in children and adolescents with type 1 diabetes.
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