Key result
Higher age and elevated diastolic BP are linked to increased microalbuminuria in young T1D patients.
Why the study?
The relationship between blood pressure and urinary albumin excretion rate in young Type 1 diabetic patients compared to non-diabetic children was not well characterized.
Population
506 boys and 441 girls with Type 1 diabetes and 663 healthy non-diabetic children
Comparison
Type 1 diabetic children vs healthy non-diabetic children
Design
Nation-wide cross-sectional study at 22 paediatric departments
Authors
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Microalbuminuria screening detects early nephropathy risk in pediatric T1D; leaves open its prognostic value and management implications.
Cross-Sectional (n=1,610)
Yes
Elevated arterial blood pressure, specifically diastolic blood pressure, is associated with an increased prevalence of microalbuminuria in adolescents with Type 1 diabetes.
Mortensen et al. (1994) conducted a cross-sectional in Type 1 diabetes (n=1,610). Type 1 diabetes vs. Healthy non-diabetic children was evaluated on Elevated urinary albumin levels (microalbuminuria). Age and elevated diastolic blood pressure were the only risk determinants for elevated urinary albumin levels in young patients with Type 1 diabetes.
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