Key result
Increased albumin excretion rate in type I diabetes was significantly associated with increased serum creatinine and blood pressure after 10 years of disease duration (P<0.005).
Cross-Sectional (n=166)
No
p-value: p=<0.005
In patients with type I diabetes, increased albumin excretion rate is significantly linked to declining renal function and increased blood pressure after a 10-year latent period.
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May inform risk stratification after 10 years in type 1 diabetes; leaves open causality and need for prospective trials.
Wiegmann et al. (1992) conducted a cross-sectional in Type I diabetes mellitus (n=166). Increased albumin excretion rate and disease duration vs. Normal albumin excretion rate / shorter disease duration was evaluated on Serum creatinine and blood pressure levels (p=<0.005). Increased albumin excretion rate in type I diabetes was significantly associated with increased serum creatinine and blood pressure after 10 years of disease duration (P<0.005).
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