Key result
Elevated urinary albumin (>15 micrograms/min) and high glomerular filtration rate (>150 ml/min) are major determinants for subsequent progression to nephropathy in patients with diabetes.
Population
Patients with type I and type II diabetes. The report includes four studies: a cross-sectional study of 56…
Design
Review
Follow-up
More than 7 years
Authors
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Cross-sectional links between BP and renal function in type 1 diabetes remain hypothesis-generating; prospective studies needed to clarify causality.
Elevated urinary albumin and high glomerular filtration rate are key predictors of progression to diabetic nephropathy and mortality, whereas high blood pressure may not be a major initial determinant.
Mogensen et al. (1985) conducted a review in Diabetic nephropathy. Elevated urinary albumin and high glomerular filtration rate was evaluated on Progression to nephropathy, development of proteinuria, and early mortality. Elevated urinary albumin (>15 micrograms/min) and high glomerular filtration rate (>150 ml/min) are major determinants for subsequent progression to nephropathy in patients with diabetes.
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