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September 1, 1968CirculationOpen Access

Hemolytic Anemia Due to Progressive Enlargement of Silastic Ball Component of Aortic Prosthesis

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Key result

Progressive enlargement of the Silastic ball component of a Starr-Edwards aortic prosthesis caused severe hemolytic anemia, which disappeared after the prosthesis was replaced with a homograft valve.

Population

1 patient who developed hemolytic anemia following insertion of a Starr-Edwards aortic valve prosthesis

Design

Case_report

Authors

MGMARIO C. GARCIAUniversity of MinnesotaACAlbert ClarysseUniversity of MinnesotaCACarl S. AlexanderUniversity of Minnesota

Discussion

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Implication

May prompt evaluation for ball enlargement in unexplained hemolytic anemia after Starr-Edwards implantation; leaves open need for systematic surveillance in this population.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
1 patient who developed severe hemolytic anemia due to progressive enlargement of the Silastic ball component of a Starr-Edwards aortic prosthesis.
E
Exposure
Replacement of the prosthesis with a homograft valve
O
Outcome
Resolution of hemolysis

Highlights a rare complication of Starr-Edwards aortic valve prostheses where lipid deposition causes ball enlargement, obstruction, and hemolytic anemia, which is curable by valve replacement.

Cite This Study

GARCIA et al. (1968) conducted a case report in Hemolytic anemia (n=1). Starr-Edwards aortic valve prosthesis was evaluated on Hemolysis resolution. Progressive enlargement of the Silastic ball component of a Starr-Edwards aortic prosthesis caused severe hemolytic anemia, which disappeared after the prosthesis was replaced with a homograft valve.

synapsesocial.com/papers/6a9343852425b9901e2061dbhttps://doi.org/10.1161/01.cir.38.3.505
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early Results of Use of Homografts for Replacement of the Aortic Valve in Man1967 · 34 citations
  2. 2Homograft Aortic Valve Replacement in Aortic Incompetence and Stenosis1964 · 435 citations
  3. 3Total Cardiac Valve Replacement Using SCDK-Cutter Prosthesis1966 · 55 citations
  4. 4Severe Mechanical Hemolytic Anemia Due to Valvular Heart Disease Without Prosthesis1966 · 21 citations
  5. 5Aortic Valve Disease and Hemolytic Anemia1966 · 26 citations