Key result
Starr-Edwards prostheses (n=27) were associated with a significantly higher incidence and degree of hemolysis compared to fascia lata grafts (n=35) following aortic valve replacement.
Why the study?
Does the use of Starr-Edwards prostheses compared to fascia lata grafts affect the incidence and degree of chronic hemolysis following aortic valve replacement?
Population
62 patients investigated for chronic intravascular hemolysis following aortic valve replacement
Comparison
Starr-Edwards prostheses (n=27) vs Fascia lata grafts (n=35)
Design
Cohort
Follow-up
3 months to 6.5 years
Authors
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May prompt hemolysis surveillance with Starr-Edwards valves; leaves open applicability to contemporary prostheses.
Cohort (n=62)
Does the use of Starr-Edwards prostheses compared to fascia lata grafts affect the incidence and degree of chronic hemolysis following aortic valve replacement?
Starr-Edwards prostheses are associated with a significantly higher incidence and degree of chronic hemolysis compared to fascia lata grafts following aortic valve replacement, particularly with smaller valve sizes.
Dave et al. (1972) conducted a cohort in chronic intravascular hemolysis following aortic valve replacement (n=62). Starr-Edwards prostheses vs. fascia lata grafts was evaluated on incidence and degree of hemolysis. Starr-Edwards prostheses (n=27) were associated with a significantly higher incidence and degree of hemolysis compared to fascia lata grafts (n=35) following aortic valve replacement.
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