Key result
Heart rate variability indices did not differ significantly between patients with idiopathic dilated cardiomyopathy who did and did not experience subsequent major arrhythmic events.
Why the study?
Does heart rate variability predict major arrhythmic events in patients with idiopathic dilated cardiomyopathy?
Cohort (n=71)
Does heart rate variability predict major arrhythmic events in patients with idiopathic dilated cardiomyopathy?
Standard time- and frequency-domain HRV parameters from 24-hour Holter monitoring do not significantly predict major arrhythmic events in patients with idiopathic dilated cardiomyopathy, though trends suggest attenuated parasympathetic activity may be present.
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HRV indices should not guide arrhythmic risk stratification in idiopathic dilated cardiomyopathy; leaves open whether refined autonomic measures may add value.
Hoffmann et al. (1996) conducted a cohort in Idiopathic dilated cardiomyopathy (IDC) (n=71). Heart rate variability (HRV) vs. Normal/higher heart rate variability was evaluated on Major arrhythmic events (sustained ventricular tachycardia, ventricular fibrillation, and sudden cardiac death). Heart rate variability indices did not differ significantly between patients with idiopathic dilated cardiomyopathy who did and did not experience subsequent major arrhythmic events.
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