Key result
Subcutaneous epinephrine (0.4-15.7 micrograms/kg) administered for hemostasis during halothane anesthesia in children resulted in no ventricular dysrhythmias.
Why the study?
Does subcutaneous epinephrine cause ventricular dysrhythmias in children anesthetized with halothane?
Population
83 children without congenital heart disease anesthetized with halothane
Design
Cohort
Follow-up
Intraoperative
Authors
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Supports safe subcutaneous epinephrine use in pediatric halothane anesthesia; hypothesis-generating and requires randomized confirmation before practice change.
Observational (n=83)
Does subcutaneous epinephrine cause ventricular dysrhythmias in children anesthetized with halothane?
Subcutaneous epinephrine up to at least 10 micrograms/kg can be safely used for hemostasis in normocarbic and hypocarbic pediatric patients without congenital heart disease during halothane anesthesia.
Karl et al. (1983) conducted an observational in Halothane anesthesia (n=83). Subcutaneous epinephrine was evaluated on Ventricular dysrhythmias. Subcutaneous epinephrine (0.4-15.7 micrograms/kg) administered for hemostasis during halothane anesthesia in children resulted in no ventricular dysrhythmias.
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