Key result
Enflurane with subcutaneous epinephrine is linked to ~86% less ventricular ectopy than halothane with epinephrine.
Why the study?
Does subcutaneous epinephrine during enflurane or halothane anesthesia increase the incidence of ventricular ectopy?
Population
100 patients undergoing anesthesia requiring surgical hemostasis
Comparison
Subcutaneous epinephrine administered during… vs Halothane anesthesia with or without…
Design
Cohort
Authors
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May support enflurane with epinephrine in observational data; leaves open need for randomized confirmation before practice change.
Observational (n=100)
Does subcutaneous epinephrine during enflurane or halothane anesthesia increase the incidence of ventricular ectopy?
Absolute Event Rate: 1% vs 7%
Enflurane anesthesia with concomitant subcutaneous epinephrine is associated with a very low incidence of ventricular ectopy (1%) and appears safe compared to halothane.
Reisner et al. (1975) conducted an observational in Anesthesia (n=100). Enflurane with subcutaneous epinephrine vs. Halothane with subcutaneous epinephrine was evaluated on Ventricular ectopy. Enflurane anesthesia with subcutaneous epinephrine resulted in a 1% incidence of ventricular ectopy, compared to 7% with halothane and epinephrine.
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