Key result
Optical coherence tomography identified angiographically silent coronary abnormalities in all 5 children with Kawasaki disease and 9 of 12 pediatric heart transplant recipients.
Why the study?
Does optical coherence tomography (OCT) identify coronary abnormalities not seen by angiography in children with Kawasaki disease and pediatric heart transplant recipients?
Population
17 children, including 5 with a history of Kawasaki disease and 12 pediatric heart transplant recipients.
Comparison
Optical coherence tomography using a modified… vs Angiography
Design
Case_series
Authors
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OCT detects silent lesions in small pediatric cohorts; hypothesis-generating and should not yet change practice.
Observational (n=17)
Does optical coherence tomography (OCT) identify coronary abnormalities not seen by angiography in children with Kawasaki disease and pediatric heart transplant recipients?
OCT is feasible in children and can detect significant coronary abnormalities, such as intimal thickening and structural vessel wall changes, that are angiographically silent in pediatric patients with Kawasaki disease or heart transplants.
Harris et al. (2014) conducted an observational in Kawasaki disease and pediatric heart transplant (n=17). Optical coherence tomography vs. Angiography was evaluated on Coronary abnormalities not seen by angiography. Optical coherence tomography identified angiographically silent coronary abnormalities in all 5 children with Kawasaki disease and 9 of 12 pediatric heart transplant recipients.
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