Key result
School-aged children with a history of Kawasaki disease had significantly higher aortic pulse wave velocity and homocysteine levels compared to healthy controls, indicating increased arterial stiffness and risk for early atherosclerosis.
Why the study?
Do school-aged children with a history of Kawasaki disease have an increased risk for early atherosclerosis compared to healthy children?
Population
98 school-aged children, including 19 with Kawasaki disease with persistent or regressed coronary arterial…
Comparison
History of Kawasaki disease vs Healthy age- and sex-matched control children
Design
Cohort
Follow-up
Group A: 68.95±31.75 months after KD; Group B: 52.29±26.51…
Authors
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May support vascular monitoring in Kawasaki survivors; leaves open whether stiffness predicts events or warrants intervention.
Cohort (n=98)
No
Do school-aged children with a history of Kawasaki disease have an increased risk for early atherosclerosis compared to healthy children?
Absolute Event Rate: 1181.5% vs 966.71%
p-value: p=0.0001
School-aged children with a history of Kawasaki disease exhibit higher lipid profiles, homocysteine levels, and arterial stiffness compared to healthy controls, indicating an increased risk for early atherosclerosis.
Cho et al. (2014) conducted a cohort in Kawasaki disease (n=98). History of Kawasaki disease vs. Healthy children was evaluated on Aortic pulse wave velocity (PWV) (p=0.0001). School-aged children with a history of Kawasaki disease had significantly higher aortic pulse wave velocity and homocysteine levels compared to healthy controls, indicating increased arterial stiffness and risk for early atherosclerosis.
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