Why the study?
Do children with Kawasaki disease have persistent abnormalities in carotid intima-media thickness and lipid profile at 5-year follow-up?
Population
27 children with Kawasaki disease followed up at least 5 years after the acute episode
Design
Cohort
Follow-up
at least 5 years after the acute episode
Key result
Children with Kawasaki disease had significantly higher mean carotid intima-media thickness than controls, and 7 of 27 children demonstrated abnormal lipid profiles at 5-year follow-up.
Authors
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May support extended surveillance in Kawasaki disease survivors; leaves open prognostic value and need for prospective validation.
Cohort (n=27)
Do children with Kawasaki disease have persistent abnormalities in carotid intima-media thickness and lipid profile at 5-year follow-up?
Children with Kawasaki disease exhibit persistent subclinical atherosclerosis markers (increased cIMT) and lipid abnormalities at least 5 years post-acute episode, warranting long-term cardiovascular follow-up.
Gopalan et al. (2018) conducted a cohort in Kawasaki disease (n=27). Kawasaki disease vs. Control subjects was evaluated on Carotid intima-media thickness (cIMT) and lipid profile. Children with Kawasaki disease had significantly higher mean carotid intima-media thickness than controls, and 7 of 27 children demonstrated abnormal lipid profiles at 5-year follow-up.
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