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August 24, 1967New England Journal of Medicine

Early Reduction of Pulmonary Vascular Resistance after Mitral-Valve Replacement

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Authors

JDJames E. DalenGeneral CardiologyJMJack M. MatloffInterventional / Structural CardiologyGEGerald L. EvansMcMaster University Medical Centre

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Implication

May inform mitral stenosis risk stratification; leaves open therapeutic implications in contemporary practice.

Key Points

  • To assess early postoperative changes in calculated pulmonary vascular resistance and pulmonary artery pressure following mitral-valve replacement in patients with mitral stenosis.
  • Monitored hemodynamic parameters, focusing on pulmonary artery, pulmonary capillary, and left atrial pressures, before and after surgical mitral-valve replacement.
  • Assessed changes in pulmonary vascular resistance among patients presenting with severe pulmonary vascular disease.
  • Pulmonary vascular resistance decreases substantially during the early postoperative period after mitral-valve replacement.
  • Disproportionate elevations in pulmonary artery pressure resolve markedly once left atrial pressure is normalized via valve replacement.

Cite This Study

Dalen et al. (1967) studied this question.

synapsesocial.com/papers/6a93b1720be0ae7ae656aa51https://doi.org/10.1056/nejm196708242770801

Topics

Mitral valve intervention
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Also Consider

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  1. 1THE NATURE OF PULMONARY HYPERTENSION IN MITRAL STENOSIS1954 · 74 citations
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