Key result
Increasing the threshold coefficient during image segmentation of a cerebral aneurysm decreases the reconstructed geometry volume and significantly alters hemodynamic parameters, increasing maximum wall shear stress and velocity.
Why the study?
Patient-specific geometries for CFD in cerebrovascular disease are generally reconstructed from medical images using subjectively chosen threshold values.
Comparison
Different threshold coefficients (Cthres 0.2, 0.3, 0.4, 0.5, and 0.6) for 3D arterial geometry reconstruction
Design
Patient-specific computational fluid dynamics simulation study
Authors
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Threshold choice in CFD geometry reconstruction warrants caution in cerebrovascular assessments; leaves open need for standardized protocols in hemodynamic research.
The choice of threshold coefficient during image segmentation significantly alters the reconstructed geometry and resulting hemodynamic parameters in patient-specific computational fluid dynamics models of cerebral aneurysms.
Hong et al. (2020) studied Internal carotid artery (ICA) aneurysm (n=1). Threshold coefficient (Cthres) variation in image segmentation vs. Comparison across different Cthres values was evaluated on Geometry volume, maximum wall shear stress (WSS), and maximum velocity. Increasing the threshold coefficient during image segmentation of a cerebral aneurysm decreases the reconstructed geometry volume and significantly alters hemodynamic parameters, increasing maximum wall shear stress and velocity.
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