Key result
Increasing threshold image intensity reduces vascular model volume and increases wall shear stress, altering CFD.
Why the study?
Threshold image intensity for patient vascular models is determined instinctively, and its effect on computational fluid dynamics of patient-specific cerebral aneurysm requires evaluation.
Does the threshold image intensity level affect computational fluid dynamics and wall shear stress in patient-specific cerebral aneurysm models?
Observational (n=5)
Does the threshold image intensity level affect computational fluid dynamics and wall shear stress in patient-specific cerebral aneurysm models?
Threshold image intensity levels significantly affect computational fluid dynamics and wall shear stress calculations in patient-specific cerebral aneurysm models, highlighting the importance of objective image segmentation.
Threshold selection in aneurysm image segmentation warrants caution for CFD reliability; leaves open standardized protocols for clinical modeling.
Threshold image intensity for patient vascular models is determined instinctively. In this study, we used the simple method of threshold resolve to evaluate the effect of threshold image intensity level on computational fluid dynamics (CFD) of patient-specific cerebral aneurysm. This investigation involved five patients with internal carotid aneurysms collected in retrospect between August 2010 and October 2012. In 3-dimensional rotational angiography with digital subtraction angiography (DSA) image data, we set five straight line probe across the parent of the internal carotid artery and deliberate the average profile curve of the image intensity along this line. To determine the threshold image intensity level objectively, we calculated the threshold coefficient Cthre using this profile curve. The effect of Cthre value on vascular model configuration and the wall shear stress (WSS) distribution of the aneurysm was evaluated. Result shows for the inlet area and volume of the vascular model decreased and WSS increased according to the Cthre value increase. In one stage, the pattern of WSS distribution changed strangely and the threshold image intensity level can result reflective effects on CFD. This finding necessary to advance a further understanding of problems in image segmentation and solving the patient-specific aneurysm problems.
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Mohd Azrul Hisham Mohd Adib (2016) conducted an observational in internal carotid aneurysms (n=5). Threshold image intensity level (Cthre value) was evaluated on Vascular model configuration (inlet area and volume) and wall shear stress (WSS) distribution. Increasing the threshold image intensity level decreased the inlet area and volume of the vascular model and increased wall shear stress, significantly affecting computational fluid dynamics.
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