Key result
Varying image intensity thresholds alter vessel geometry and wall shear stress in cerebral aneurysms.
Why the study?
The influence of blood vessel geometry reconstruction on threshold image intensity levels in vessel segmentation for cerebral aneurysms is not well understood.
How do different threshold image intensity levels affect the reconstruction of blood vessel geometry and computational simulations of blood flow in a patient with a cerebral aneurysm?
How do different threshold image intensity levels affect the reconstruction of blood vessel geometry and computational simulations of blood flow in a patient with a cerebral aneurysm?
Small changes in image segmentation threshold levels can significantly alter reconstructed blood vessel geometry and subsequent computational blood flow simulations.
Threshold choice may bias aneurysm CFD hemodynamics; leaves open need for standardized segmentation validation.
Thresholding is the greenest and most generally used techniques in image segmentation. This threshold determination can be used to extract various features of the vascular geometry that is used for understanding and analyzing of the image. Our objective is to investigate the influence of the modernization of blood vessel geometry to the threshold image intensity level difference in vessel segmentation. This study included a patient with cerebral aneurysms. We employed three different threshold levels from 200, 400 and 600 in order to determine the influence of the threshold objectively. The flow solution variation on exemplified by wall shear stress (WSS) presents similarity due to the location and magnitude of geometry variation resulting from the different threshold image intensity level and relatively small changes can lead to important dissimilarity in geometry of vessel and flow feature, predominantly in location with an enormous variety of cross sectional area. This is the significance of the understanding of modeling computational simulations of blood flow and can be expressively effected by alterations in geometry different.
No takes yet. Share an insight, caveat, or question.
Adib et al. (2015) studied cerebral aneurysms (n=1). Threshold image intensity levels (200, 400, 600) was evaluated on Wall shear stress (WSS) and geometry variation. Varying threshold image intensity levels (200, 400, and 600) led to important dissimilarities in vessel geometry and flow features like wall shear stress in a patient with cerebral aneurysms.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: