Key result
Low voltage scanning electron microscopy reveals that pyrolytic carbon mechanical heart valve leaflets are rough at submicron scales and induce extensive platelet spreading in vitro.
Population
Explanted prosthetic mechanical heart valves made from pyrolytic carbon from humans or research animals
Design
Review
Authors
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Submicron roughness may promote platelet spreading on pyrolytic carbon valves in vitro; hypothesis-generating and leaves open clinical thromboresistance implications.
High-resolution SEM imaging reveals that pyrolytic carbon mechanical heart valves have submicron roughness that promotes platelet spreading, challenging traditional explanations of their thromboresistance.
Goodman et al. (1998) conducted a review in Prosthetic mechanical heart valves. Pyrolytic carbon (PYC) mechanical heart valves was evaluated. Low voltage scanning electron microscopy reveals that pyrolytic carbon mechanical heart valve leaflets are rough at submicron scales and induce extensive platelet spreading in vitro.
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