Key result
Hypotonic and hypertonic solutions cause transient and permanent changes in the absorbancy of human platelet-containing plasma, which are dependent on intact platelets and sulphydryl compounds.
The osmotic response of human platelets to hypotonic solutions involves a physical initial phase and a chemical-enzymic reversal phase requiring intact platelets and sulphydryl groups.
No takes yet. Share an insight, caveat, or question.
Requires caution in platelet sample handling; leaves open in vivo osmotic effects on platelet function.
P Fantl (1968) studied this question. Hypotonic and hypertonic solutions vs. Isotonic solutions was evaluated on Absorbancy of light at 610 mmu. Hypotonic and hypertonic solutions cause transient and permanent changes in the absorbancy of human platelet-containing plasma, which are dependent on intact platelets and sulphydryl compounds.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: