Key result
Among 401 critically ill patients not treated with cardiac glycosides, 14.5% had positive endogenous digitalis-like-immunoreactive substances, which correlated with severity of illness scores.
Population
401 consecutive critically ill patients not treated with cardiac glycosides in two surgical intensive care…
Design
Cohort
Authors
Loading...
Endogenous digitalis-like substances may mark greater illness severity in the ICU; leaves open causal role and any clinical utility.
Observational (n=401)
No
Critically ill patients frequently exhibit elevated endogenous digitalis-like substances and ouabain, which correlate with illness severity and systemic inflammation.
Berendes et al. (2003) conducted an observational in Critically ill (n=401). Endogenous digitalis-like-immunoreactive substances (DLIS) vs. DLIS-negative patients and healthy volunteers was evaluated on Incidence of positive DLIS concentrations. Among 401 critically ill patients not treated with cardiac glycosides, 14.5% had positive endogenous digitalis-like-immunoreactive substances, which correlated with severity of illness scores.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: